caspase activity determination
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http://www.bioassayontology.org/bao#BAO_0000165
Caspases are cysteine proteases which play an important role in apoptosis. They are synthesized and stored in cells as inactive procaspases. Once apoptosis is initiated in a cell, the procaspases get activated by proteolytic cleavage. This sets in motion a caspase cascade, which leads to the activation of proteins involved in the chromatin fragmentation and finally culminates in cell death.
Term info
Label
caspase activity determination
Term relations
Subclass of:
- viability measurement method
- has participant some DEVD-NucView 488
- has detection method some fluorescence microscopy
- has measured entity some (
Caspase-3 and
has substrate some DEVD-NucView 488)
Related from: