Terminology Service for NFDI4Health
Ac-WEHD-CHO
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http://www.bioassayontology.org/bao#BAO_0000837
Ac-Trp-Glu-His-Asp-CHO Very potent reversible inhibitor of caspase-1 (ICE) that contains the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM, it displays the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.