All terms in BAO
Label | Id | Description |
---|---|---|
osteochondrosis | DOID_8125 | [An ischemic bone disease that results_in necrosis followed by regrowth in children and teens located_in bone.] |
high signal control | BAO_0000156 | [The role played by the substrate, which is titrated without inhibitor to reflect the maximum enzyme activity at each substrate concentration.] |
fluorescent protein induction | BAO_0000153 | [Fluorescent proteins are commonly used as reporter genes to study the effect of perturbagens on gene expression. Examples include green fluorescent protein (GFP) from the jellyfish Aequorea victoria and the various modifications of it created by amino acid substitutions to either optimize the codon usage in mammalian cells or to change the spectral properties of the protein.] |
luciferase induction | BAO_0000152 | [Luciferase gene is attached to the regulatory sequence of a gene of interest. The effect of a perturbagen on the expression of the gene of interest could be easily measured by the detection of light emitted as a product the luciferase reaction.] |
beta lactamase induction | BAO_0000151 | [Beta lactamase gene is attached to the regulatory sequence of a gene of interest. The effect of a perturbagen on the expression of the gene of interest could be easily monitored by the detection of the product of beta lactamase enzyme.] |
beta galactosidase induction | BAO_0000150 | [Beta galactosidase gene is attached to the regulatory sequence of a gene of interest. The effect of a perturbagen on the expression of the gene of interest could be easily monitored by the detection of the product of beta galactosidase enzyme.] |
chromatin condensation visualization | BAO_0000159 | [Chromatin condensation is one of the morphological changes that occur during apoptosis. It is also known as pyknosis and can be visualized by staining with dyes followed by microscopy.] |
esterase activity determination | BAO_0000158 | [Cell viability can be assessed by the presence of cytoplasmic esterases that cleave a lipid-soluble nonfluorescent probe to yield a fluorescent product. The product is charged and is thus retained within the cell if the membrane is intact. Typical probes include fluorescein diacetate (FDA), carboxyfluorescein, and calcein.] |
gut flora metabolite | CHEBI_82933 | |
metabolite | CHEBI_25212 | |
Reye syndrome | DOID_14525 | [A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.] |
syndrome | DOID_225 | [A disease comprised of a group of signs and symptoms that occur together and characterize a particular abnormality.] |
A549 cell | CLO_0001601 | |
intestinal perforation | DOID_2074 | |
intestinal disease | DOID_5295 | [A gastrointestinal system disease that is located_in the intestine.] |
substernal goiter | DOID_13200 | |
goiter | DOID_12176 | [A thyroid gland disease that involves an abnormal enlargement of the thyroid gland.] |
proliferative diabetic retinopathy | DOID_13207 | |
diabetic retinopathy | DOID_8947 | |
right bundle branch block | DOID_13209 |