Terminology Service for NFDI4Health
JSON

cycloguanil

Go to external page http://purl.obolibrary.org/obo/CHEBI_135029

A triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil.

Term info

Label

cycloguanil

Synonyms
  • 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine
database cross reference
Subsets

3_STAR

IUPAC NAME
1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine [ IUPAC ]

charge

0

formula

C11H14ClN5

has obo namespace

chebi_ontology

has related synonym

1-(p-chlorophenyl)-4,6-diamino-2,2-dimethyl-1,2-dihydro-s-triazine, Chlorcycloguanil

id

CHEBI:135029

inchi

InChI=1S/C11H14ClN5/c1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8/h3-6H,1-2H3,(H4,13,14,15,16)

inchikey

QMNFFXRFOJIOKZ-UHFFFAOYSA-N

mass

251.716

monoisotopicmass

251.09377

smiles

C1(N(C(N)=NC(=N1)N)C2=CC=C(C=C2)Cl)(C)C