Terminology Service for NFDI4Health
JSON

RF9

Go to external page http://purl.obolibrary.org/obo/CHEBI_140980

A dipeptide formed from L-arginine and L-phenylalaninamide residues in which a hydrogen attached to the nitrogen of the alpha-amino group of the arginine residue has been replaced by a 1-adamantanecarbonyl group. It has been reported to be a potent and selective antagonist of neuropeptide FF (NPFF) receptors, but more recently found to be an agonist at both NPFF1R and the kisspeptin receptor (KISS1R).

Term info

Label

RF9

Synonyms
  • N(2)-(tricyclo[3.3.1.1(3,7)]decan-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide
database cross reference
Subsets

3_STAR

IUPAC NAME
N(2)-(tricyclo[3.3.1.1(3,7)]decan-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide [ IUPAC ]

charge

0

formula

C26H38N6O3

has obo namespace

chebi_ontology

has related synonym

neuropeptide FF receptor antagonist, NPFF receptor antagonist, RF-9, 1-adamantanecarbonyl-Arg-Phe-NH2, RF 9

id

CHEBI:140980

inchi

InChI=1S/C26H38N6O3/c27-22(33)21(12-16-5-2-1-3-6-16)31-23(34)20(7-4-8-30-25(28)29)32-24(35)26-13-17-9-18(14-26)11-19(10-17)15-26/h1-3,5-6,17-21H,4,7-15H2,(H2,27,33)(H,31,34)(H,32,35)(H4,28,29,30)/t17?,18?,19?,20-,21-,26?/m0/s1

inchikey

UMKHUSRDQFQHAK-RNJMTYCLSA-N

mass

482.619

monoisotopicmass

482.30054

smiles

O=C(N[C@@H](CC1=CC=CC=C1)C(N)=O)[C@@H](NC(=O)C23CC4CC(C2)CC(C3)C4)CCCNC(=N)N