Terminology Service for NFDI4Health

tipifarnib

Go to external page http://purl.obolibrary.org/obo/CHEBI_141969


A quinolone that is 1-methylquinolin-2-one which carries a 3-chlorophenyl and an amino(4-chlorophenyl)(1-methyl-imidazol-5-yl)methyl groups at the 4 and 6 positions, respectively (the R-isomer).

Term info

Label

tipifarnib

Synonyms
  • 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one
database cross reference
Subsets

3_STAR

INN
tipifarnib [ WHO_MedNet ]

BRAND NAME
Zarnestra [ DrugBank ]

INN
tipifarnibum [ WHO_MedNet ]

IUPAC NAME
6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one [ IUPAC ]

charge

0

formula

C27H22Cl2N4O

has obo namespace

chebi_ontology

has related synonym

Zarnestra, R115777, (R)-6-(amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone, tipifarnib, R-115777, tipifarnibum, (+)-(R)-6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone

id

CHEBI:141969

inchi

InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1

inchikey

PLHJCIYEEKOWNM-HHHXNRCGSA-N

mass

489.397

monoisotopicmass

488.11707

smiles

C1(C=C(C2=C(N1C)C=CC(=C2)[C@](C=3C=CC(=CC3)Cl)(C4=CN=CN4C)N)C=5C=C(C=CC5)Cl)=O