spectinabilin
A polyketide that is deoxyspectinabilin in which the tetramethyldeca-tetraen-1-yl chain attached to the 4-pyranone moiety has undergone oxidation at position 1 and at the methyl group at position 3 to afford the corresponding tetrahydrofuranyl moiety. Produced by Streptomyces spectabilis, it exhibits antiviral and antimalarial activity.
Term info
spectinabilin
- 2-methoxy-3,5-dimethyl-6-{(2R,4Z)-4-[(2E,4E,6E)-2,4,6-trimethyl-7-(4-nitrophenyl)hepta-2,4,6-trien-1-ylidene]tetrahydrofuran-2-yl}-4H-pyran-4-one
- spectinabilin
3_STAR
0
C28H31NO6
chebi_ontology
(+)-neoaureothin, neoaureothin, (+)-spectinabilin
CHEBI:142841
InChI=1S/C28H31NO6/c1-17(11-18(2)13-22-7-9-24(10-8-22)29(31)32)12-19(3)14-23-15-25(34-16-23)27-20(4)26(30)21(5)28(33-6)35-27/h7-14,25H,15-16H2,1-6H3/b17-11+,18-13+,19-12+,23-14-/t25-/m1/s1
IZICQJAGBLBAMJ-QDYRYYKCSA-N
477.557
477.21514
C1=CC(=CC=C1/C=C(\C)/C=C(\C)/C=C(\C)/C=C\2/C[C@@](OC2)(C3=C(C(C(=C(O3)OC)C)=O)C)[H])[N+]([O-])=O
Term relations
- ketene acetal
- oxolanes
- polyketide
- 4-pyranones
- C-nitro compound
- has role some antiplasmodial drug
- has functional parent some deoxyspectinabilin
- has role some antiviral agent
- has role some nematicide
- has role some bacterial metabolite