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puromycin

Go to external page http://purl.obolibrary.org/obo/CHEBI_17939

An aminonucleoside antibiotic, derived from the Streptomyces alboniger bacterium, that causes premature chain termination during translation taking place in the ribosome.

Term info

Label

puromycin

Synonyms
  • 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine
  • Puromycin
database cross reference
Subsets

3_STAR

INN
puromycin [ ChemIDplus ]

INN
puromicina [ ChemIDplus ]

INN
puromycine [ ChemIDplus ]

INN
puromycinum [ ChemIDplus ]

IUPAC NAME
3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine [ IUPAC ]

charge

0

formula

C22H29N7O5

has alternative id

CHEBI:45182, CHEBI:14970, CHEBI:26402, CHEBI:8641

has obo namespace

chebi_ontology

has related synonym

puromycine, puromycinum, 9-{3-deoxy-3-[(O-methyl-L-tyrosyl)amino]-beta-D-xylofuranosyl}-N,N-dimethyl-9H-purin-6-amine, 3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-diemthyladenosine, (S)-3'-((2-Amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyladenosine, Achromycin, puromycin, 3'-(L-alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine, puromicina

id

CHEBI:17939

inchi

InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1

inchikey

RXWNCPJZOCPEPQ-NVWDDTSBSA-N

mass

471.50984

monoisotopicmass

471.22302

smiles

COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1