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desloratadine

Go to external page http://purl.obolibrary.org/obo/CHEBI_291342

Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.

Term info

Label

desloratadine

Synonyms
  • 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • DESLORATADINE
database cross reference
Subsets

3_STAR

IUPAC NAME
8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine [ IUPAC ]

INN
desloratadine [ KEGG_DRUG ]

charge

0

formula

C19H19ClN2

has obo namespace

chebi_ontology

has related synonym

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine, descarboethoxyloratadine, desloratadine

id

CHEBI:291342

inchi

InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2

inchikey

JAUOIFJMECXRGI-UHFFFAOYSA-N

mass

310.82100

monoisotopicmass

310.12368

smiles

Clc1ccc2c(CCc3cccnc3C2=C2CCNCC2)c1