Terminology Service for NFDI4Health
JSON

fluorometholone

Go to external page http://purl.obolibrary.org/obo/CHEBI_31625

A member of the class of glucocorticoids that is Delta(1)-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

Term info

Label

fluorometholone

Synonyms
  • (6alpha,11beta)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
  • 9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
database cross reference
Subsets

3_STAR

BRAND NAME
Oxylone [ KEGG_DRUG ]

INN
fluorometholone [ DrugBank ]

INN
fluorometholone [ KEGG_DRUG ]

INN
fluorometholonum [ DrugBank ]

BRAND NAME
Fluor-op [ KEGG_DRUG ]

IUPAC NAME
(6alpha,11beta)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione [ IUPAC ]

IUPAC NAME
9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione [ IUPAC ]

INN
fluorometolona [ DrugBank ]

charge

0

formula

C22H29FO4

has obo namespace

chebi_ontology

has related synonym

fluorometolona, NSC 33001, Fluor-op, Oxylone, fluorometholone, fluorometholonum, 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione, Fluorometholon

id

CHEBI:31625

inchi

InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1

inchikey

FAOZLTXFLGPHNG-KNAQIMQKSA-N

mass

376.46170

monoisotopicmass

376.20499

smiles

C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]2(C)C=CC(=O)C=C12