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glafenine

Go to external page http://purl.obolibrary.org/obo/CHEBI_31653

A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.

Term info

Label

glafenine

Synonyms
  • 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate
database cross reference
Subsets

3_STAR

INN
glafenina [ ChemIDplus ]

INN
glafenine [ WHO_MedNet ]

INN
glafenine [ KEGG_DRUG ]

INN
glafeninum [ ChemIDplus ]

IUPAC NAME
2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate [ IUPAC ]

charge

0

formula

C19H17ClN2O4

has alternative id

CHEBI:344737

has obo namespace

chebi_ontology

has related synonym

glafeninum, Glifan, 2,3-Dihydroxypropyl N-(7-chloro-4-quinolyl) anthranilate, Glaphenine, Glycerylaminophenaquine, Glifanan, Glicafan, glafenine, glafenina, 4-((2-Carboxyphenyl)amino)-7-chloroquinoline alpha-monoglyceride, 4-(2'-beta,gamma-Dihydroxypropoxycarbonylphenylamino)-7-chloroquinoline, Glaphenin, Glafenin

id

CHEBI:31653

inchi

InChI=1S/C19H17ClN2O4/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23/h1-9,13,23-24H,10-11H2,(H,21,22)

inchikey

GWOFUCIGLDBNKM-UHFFFAOYSA-N

mass

372.80200

monoisotopicmass

372.08768

smiles

OCC(O)COC(=O)c1ccccc1Nc1ccnc2cc(Cl)ccc12