dapsone
A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy.
Term info
dapsone
- 4,4'-sulfonyldianiline
- DAPSONE
- Dapsone
3_STAR
0
C12H12N2O2S
CHEBI:226356
chebi_ontology
Diaphenylsulfone, 4,4'-dapsone, 4,4'-Sulfonylbisbenzenamine, p,p-sulphonylbisbenzamine, DIAPHENYLSULFONE, bis(4-aminophenyl)sulfone, p-aminophenyl sulfone, p,p'-diaminodiphenyl sulfone, dapsonum, 4-(4-aminophenylsulfonyl)benzenamine, DDS, dapsone, 1,1'-sulfonylbis(4-aminobenzene), 4-(4-aminophenylsulfonyl)aniline, DADPS, dapsona, 4-aminophenyl sulfone, Bis(p-aminophenyl) sulfone, p,p-sulphonylbisbenzenamine, 4,4'-diaminodiphenyl sulfone, 4-(4-amino-benzenesulfonyl)-phenylamine, 4,4'-sulfonylbisaniline
CHEBI:4325
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
MQJKPEGWNLWLTK-UHFFFAOYSA-N
248.30100
248.06195
Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
Term relations
- sulfone
- substituted aniline
- has functional parent some diphenyl sulfone
- has role some antiinfective agent
- has role some leprostatic drug
- has role some antimalarial
- has role some anti-inflammatory drug