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hydroxychloroquine

Go to external page http://purl.obolibrary.org/obo/CHEBI_5801

An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Term info

Label

hydroxychloroquine

Synonyms
  • 2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol
database cross reference
Subsets

3_STAR

INN
hydroxychloroquine [ ChemIDplus ]

INN
hidroxicloroquina [ ChemIDplus ]

INN
hydroxychloroquinum [ ChemIDplus ]

BRAND NAME
Polirreumin [ KEGG_DRUG ]

IUPAC NAME
2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol [ IUPAC ]

INN
hydroxychloroquine [ WHO_MedNet ]

charge

0

formula

C18H26ClN3O

has obo namespace

chebi_ontology

has related synonym

7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline, hydroxychloroquinum, 7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline, 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline, NSC4375, 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol, oxichloroquine, hydroxychloroquine, oxichlorochine, Polirreumin, 7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline, (+-)-hydroxychloroquine, hidroxicloroquina, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol

id

CHEBI:5801

inchi

InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)

inchikey

XXSMGPRMXLTPCZ-UHFFFAOYSA-N

mass

335.87200

monoisotopicmass

335.17644

smiles

CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12