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leflunomide

Go to external page http://purl.obolibrary.org/obo/CHEBI_6402

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Term info

Label

leflunomide

Synonyms
  • 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
  • Leflunomide
database cross reference
Subsets

3_STAR

IUPAC NAME
5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide [ IUPAC ]

BRAND NAME
Arava [ KEGG_DRUG ]

INN
leflunomidum [ WHO_MedNet ]

INN
leflunomida [ WHO_MedNet ]

INN
leflunomide [ WHO_MedNet ]

charge

0

formula

C12H9F3N2O2

has obo namespace

chebi_ontology

has related synonym

5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide, leflunomide, Arava, leflunomida, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide, leflunomidum, alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide

id

CHEBI:6402

inchi

InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)

inchikey

VHOGYURTWQBHIL-UHFFFAOYSA-N

mass

270.20730

monoisotopicmass

270.06161

smiles

Cc1oncc1C(=O)Nc1ccc(cc1)C(F)(F)F