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fluticasone furoate

Go to external page http://purl.obolibrary.org/obo/CHEBI_74899

A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease.

Term info

Label

fluticasone furoate

Synonyms
  • 6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl 2-furoate
database cross reference
Subsets

3_STAR

INN
furoate de fluticasone [ WHO_MedNet ]

BRAND NAME
Veramyst [ KEGG_DRUG ]

INN
fluticasone furoate [ KEGG_DRUG ]

IUPAC NAME
6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl 2-furoate [ IUPAC ]

INN
furoato de fluticasona [ WHO_MedNet ]

INN
fluticasonum furoas [ WHO_MedNet ]

charge

0

formula

C27H29F3O6S

has obo namespace

chebi_ontology

has related synonym

fluticasone furoate, GSK 685698, Veramyst, furoate de fluticasone, fluticasonum furoas, furoato de fluticasona

id

CHEBI:74899

inchi

InChI=1S/C27H29F3O6S/c1-14-9-16-17-11-19(29)18-10-15(31)6-7-24(18,2)26(17,30)21(32)12-25(16,3)27(14,23(34)37-13-28)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1

inchikey

XTULMSXFIHGYFS-VLSRWLAYSA-N

mass

538.57600

monoisotopicmass

538.16369

smiles

[H][C@@]12C[C@@H](C)[C@](OC(=O)c3ccco3)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C