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naproxcinod

Go to external page http://purl.obolibrary.org/obo/CHEBI_76254

A carboxylic ester obtained by formal condensation of the carboxy group of naproxen with the hydroxy group of 4-(nitrooxy)butanol. A cyclooxygenase-inhibiting nitric oxide donator that is metabolised to naproxen and a nitric oxide donating moiety, effective in treatment of osteoarthritis.

Term info

Label

naproxcinod

Synonyms
  • 4-(nitrooxy)butyl (2S)-2-(6-methoxy-2-naphthyl)propanoate
database cross reference
Subsets

3_STAR

IUPAC NAME
4-(nitrooxy)butyl (2S)-2-(6-methoxy-2-naphthyl)propanoate [ IUPAC ]

INN
naproxcinod [ KEGG_DRUG ]

INN
naproxcinodum [ WHO_MedNet ]

INN
naproxcinod [ WHO_MedNet ]

charge

0

formula

C18H21NO6

has obo namespace

chebi_ontology

has related synonym

AZD 3582, Naproxen-N-butyl nitrate, naproxcinod, naproxcinodum, AZD3582, (S)-2-(6-Methoxy-2-naphthyl)propanoic acid 4-nitrooxybutyl ester, Nitronaproxen, HCT 3012

id

CHEBI:76254

inchi

InChI=1S/C18H21NO6/c1-13(18(20)24-9-3-4-10-25-19(21)22)14-5-6-16-12-17(23-2)8-7-15(16)11-14/h5-8,11-13H,3-4,9-10H2,1-2H3/t13-/m0/s1

inchikey

AKFJWRDCWYYTIG-ZDUSSCGKSA-N

mass

347.36240

monoisotopicmass

347.13689

smiles

COc1ccc2cc(ccc2c1)[C@H](C)C(=O)OCCCCO[N+]([O-])=O