Terminology Service for NFDI4Health
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macitentan

Go to external page http://purl.obolibrary.org/obo/CHEBI_76607

A member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension.

Term info

Label

macitentan

Synonyms
  • N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]-N'-propylsulfuric diamide
database cross reference
Subsets

3_STAR

IUPAC NAME
N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]-N'-propylsulfuric diamide [ IUPAC ]

INN
macitentanum [ WHO_MedNet ]

BRAND NAME
OPSUMIT [ KEGG_DRUG ]

INN
macitentan [ ChemIDplus ]

INN
macitentan [ WHO_MedNet ]

charge

0

formula

C19H20Br2N6O4S

has obo namespace

chebi_ontology

has related synonym

macitentanum, ACT 064992, ACT064992, macitentan, ACT-064992, OPSUMIT

id

CHEBI:76607

inchi

InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)

inchikey

JGCMEBMXRHSZKX-UHFFFAOYSA-N

mass

588.27300

monoisotopicmass

585.96335

smiles

CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1