Terminology Service for NFDI4Health
ofloxacin
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http://purl.obolibrary.org/obo/CHEBI_7731
An oxazinoquinolone carrying carboxy, fluoro, methyl and 4-methylpiperazino substituents. A synthetic fluoroquinolone antibacterial agent, it inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Term info
Label
ofloxacin
Synonyms
- 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
Subsets
3_STAR
IUPAC NAME
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
[
IUPAC
]
charge
0
formula
C18H20FN3O4
has alternative id
CHEBI:100146
has obo namespace
chebi_ontology
has related synonym
ofloxacin, ofloxacino, OFLX, ofloxacinum, ofloxacine, 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
id
CHEBI:7731
inchi
InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
inchikey
GSDSWSVVBLHKDQ-UHFFFAOYSA-N
mass
361.36750
monoisotopicmass
361.14378
smiles
CC1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O