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temafloxacin

Go to external page http://purl.obolibrary.org/obo/CHEBI_77788

A racemate comprising equimolar amounts of (R)- and (S)-temafloxacin. Both enantiomers both exhibit similar pharmacological profiles. Temafloxacin was briefly used (either as the free base or as the hydrochloride salt) as an antibacterial drug but was withdrawn worldwide in 1992 following reports of serious side effects, including severe hypoglycaemia, haemolytic anaemia, liver and kidney dysfunction, anaphylaxis, and death.

Term info

Label

temafloxacin

Synonyms
  • rac-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
database cross reference
Subsets

3_STAR

INN
temafloxacinum [ WHO_MedNet ]

INN
temafloxacine [ WHO_MedNet ]

INN
temafloxacin [ WHO_MedNet ]

INN
temafloxacino [ WHO_MedNet ]

IUPAC NAME
rac-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid [ IUPAC ]

has obo namespace

chebi_ontology

has related synonym

temafloxacine, T 1258, temafloxacin, temafloxacinum, A 62254, rac-temafloxacin, (+-)-temafloxacin, temafloxacino, (+-)-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

id

CHEBI:77788