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potassium clavulanate

Go to external page http://purl.obolibrary.org/obo/CHEBI_85264

A potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes and has only weak anitbiotic activity when administered alone. However it can be used in combination with amoxicillin trihydrate (under the trade name Augmentin) for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases.

Term info

Label

potassium clavulanate

Synonyms
  • potassium (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
database cross reference
Subsets

3_STAR

IUPAC NAME
potassium (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate [ IUPAC ]

charge

0

formula

C8H8KNO5

has obo namespace

chebi_ontology

has related synonym

Clavulanate potassium, CVA

id

CHEBI:85264

inchi

InChI=1S/C8H9NO5.K/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h1,6-7,10H,2-3H2,(H,12,13);/q;+1/p-1/b4-1-;/t6-,7-;/m1./s1

inchikey

ABVRVIZBZKUTMK-JSYANWSFSA-M

mass

237.25110

monoisotopicmass

237.00395

smiles

[K+].OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C([O-])=O