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pyrimethamine

Go to external page http://purl.obolibrary.org/obo/CHEBI_8673

An aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis.

Term info

Label

pyrimethamine

Synonyms
  • 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
database cross reference
Subsets

3_STAR

INN
pyrimethaminum [ ChemIDplus ]

INN
pyrimethamine [ ChemIDplus ]

IUPAC NAME
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine [ IUPAC ]

INN
pyrimethamine [ WHO_MedNet ]

INN
pirimetamina [ ChemIDplus ]

charge

0

formula

C12H13ClN4

has obo namespace

chebi_ontology

has related synonym

Diaminopyritamin, 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine, CD, pyrimethamine, Primethamine, 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine, Chloridine, 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, Ethylpyrimidine, pyrimethaminum, pirimetamina, 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine, 2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine, 5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine, Chloridyn

id

CHEBI:8673

inchi

InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)

inchikey

WKSAUQYGYAYLPV-UHFFFAOYSA-N

mass

248.71100

monoisotopicmass

248.08287

smiles

CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1