Terminology Service for NFDI4Health
tramadol
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http://purl.obolibrary.org/obo/CHEBI_9648
A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia.
Term info
Label
tramadol
Synonyms
- rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
Subsets
3_STAR
charge
0
formula
C16H25NO2
has obo namespace
chebi_ontology
has related synonym
U-26225A, tramadolum, tramadol, E-265, CG-315E, (+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
id
CHEBI:9648
mass
263.37520
monoisotopicmass
263.18853
Term relations
Subclass of:
- racemate
- has role some adrenergic uptake inhibitor
- has role some muscarinic antagonist
- has role some NMDA receptor antagonist
- is conjugate base of some tramadol(1+)
- has role some opioid analgesic
- has role some capsaicin receptor antagonist
- has part some (S,S)-tramadol
- has role some delta-opioid receptor agonist
- has part some (R,R)-tramadol
- has role some nicotinic antagonist
- has role some kappa-opioid receptor agonist
- has role some xenobiotic
- has role some antitussive
- has role some environmental contaminant
- has role some serotonergic antagonist
- has role some mu-opioid receptor agonist
- has role some serotonin uptake inhibitor
Related from: