directly negatively regulates
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http://purl.obolibrary.org/obo/RO_0002630
Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.
Property info
OBO foundry unique label
directly negatively regulates (process to process)
definition source
http://purl.obolibrary.org/obo/ro/docs/causal-relations
is negative form of
http://purl.obolibrary.org/obo/RO_0002578