Terminology Service for NFDI4Health
monoblast
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http://purl.obolibrary.org/obo/CL_0000040
A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. [ http://www.copewithcytokines.de http://www.ncbi.nlm.nih.gov/pubmed/1104740 http://en.wikipedia.org/wiki/Monoblast ]
Term info
Label
monoblast
comment
Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.
has obo namespace
cell
has related synonym
CFU-M, colony forming unit macrophage, colony forming unit monocyte, monocyte stem cell
Term relations
Equivalent to:
- monopoietic cell and has_part some basophilic cytoplasm and has_part some euchromatin and has_part some nucleolus and has plasma membrane part some integrin alpha-M and capable of some monocyte differentiation
Subclass of:
- monopoietic cell
- material anatomical entity
- myeloid cell
- has_part some basophilic cytoplasm
- has plasma membrane part some integrin alpha-M
- has_part some euchromatin
- develops from some macrophage dendritic cell progenitor
- has_part some nucleolus
Related from: