Terminology Service for NFDI4Health
mature basophil
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http://purl.obolibrary.org/obo/CL_0000043
A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. [ http://www.ncbi.nlm.nih.gov/pubmed/19231594 http://www.cap.org http://www.ncbi.nlm.nih.gov/pubmed/20837449 http://www.ncbi.nlm.nih.gov/pubmed/18466030 https://www.worldcat.org/search?q=bn%3A0721601464 ]
Term info
Label
mature basophil
Synonyms
- mature basophil leucocyte
- mature basophil leukocyte
comment
Mature basophils are also capable of producing IL-3, IL-5, IL-6, IL-8, IL-13, IL-25, CCL22, tslp, vegf, and LTC4.
has alternative id
CL:0000739
has broad synonym
polymorphonuclear leucocyte, polymorphonuclear leukocyte
has obo namespace
cell
Term relations
Equivalent to:
- basophil and has_part some lobed nucleus and capable of some histamine production involved in inflammatory response and capable of some serotonin production involved in inflammatory response and capable of some positive regulation of type 2 immune response and capable of some blood circulation and capable of some interleukin-13 production and capable of some interleukin-4 production and capable of some positive regulation of isotype switching to IgE isotypes
Subclass of:
- histamine secreting cell
- basophil
- nucleate cell
- capable of some interleukin-4 production
- capable of some histamine production involved in inflammatory response
- capable of some positive regulation of type 2 immune response
- capable of some interleukin-13 production
- capable of some positive regulation of isotype switching to IgE isotypes
- capable of some serotonin production involved in inflammatory response
- has_part some lobed nucleus
- develops from some band form basophil