Terminology Service for NFDI4Health
T-helper 1 cell
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http://purl.obolibrary.org/obo/CL_0000545
A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. [ http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/22343568 http://www.ncbi.nlm.nih.gov/pubmed/19375293 http://www.ncbi.nlm.nih.gov/pubmed/20303875 ]
Term info
Label
T-helper 1 cell
Synonyms
- T helper cells type 1
- T(H)-1 cell
- Th1 CD4+ T cell
- Th1 T cell
- Th1 T lymphocyte
- Th1 T-cell
- Th1 T-lymphocyte
- Th1 cell
- helper T cell type 1
comment
This cell type is compatible with the HIPC Lyoplate markers for 'Th1 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 1 T cells.
has obo namespace
cell
Term relations
Equivalent to:
- CD4-positive helper T cell and has_part some T-box transcription factor TBX21 and has plasma membrane part some C-X-C chemokine receptor type 3 and capable of some interferon-gamma production and lacks_plasma_membrane_part some C-C chemokine receptor type 6