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megakaryocyte progenitor cell

http://purl.obolibrary.org/obo/CL_0000553

The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). [ https://www.worldcat.org/search?q=bn%3A0721601464 ]

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Term info

Label

megakaryocyte progenitor cell

Synonyms

CFU-Meg
Meg-CFC
MkP
colony-forming unit-megakaryocyte
megacaryoblast
megacaryocyte progenitor cell
megakaryoblast
megakaryocytic progenitor cell

database cross reference

comment

Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.

has obo namespace

cell

has related synonym

promegakaryocyte, promegacaryocyte

Term relations

Equivalent to:

myeloid lineage restricted progenitor cell and capable of some endomitotic cell cycle and capable of some megakaryocyte differentiation and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some CD2 molecule and lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some T-cell surface glycoprotein CD5 and lacks_plasma_membrane_part some CD14 molecule and lacks_plasma_membrane_part some lymphocyte antigen 6G and lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse)

Subclass of:

Related from:

develops_from

megakaryocyte