Terminology Service for NFDI4Health
monocyte
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http://purl.obolibrary.org/obo/CL_0000576
Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. [ http://purl.obolibrary.org/obo/go/references/0000031 ]
Term info
Label
monocyte
comment
Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid.
has obo namespace
cell
Term relations
Equivalent to:
- myeloid leukocyte and bearer of some mononucleate and capable of some macrophage differentiation and capable of some osteoclast differentiation and capable of some myeloid dendritic cell differentiation and lacks_part some secretory granule
Subclass of:
- mononuclear cell
- myeloid leukocyte
- precursor cell
- develops from some promonocyte
- capable of some myeloid dendritic cell differentiation
- capable of some macrophage differentiation
- capable of some osteoclast differentiation
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