Terminology Service for NFDI4Health
neutrophilic myelocyte
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http://purl.obolibrary.org/obo/CL_0000580
A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and neutrophil-specific granules has started. No nucleolus is present. This cell type is CD13-positive, CD16-negative, integrin alpha-M-positive, CD15-positive, CD33-positive, CD24-positive, C/EBP-a-positive, C/EBPe-positive, PU.1-positive, lactotransferrin-positive, myeloperoxidase-positive and NGAL-positive. [ http://www.ncbi.nlm.nih.gov/pubmed/12560239 http://www.ncbi.nlm.nih.gov/pubmed/10618520 http://www.ncbi.nlm.nih.gov/pubmed/15514007 http://www.cap.org https://www.worldcat.org/search?q=bn%3A0721601464 ]
Term info
Label
neutrophilic myelocyte
comment
These cells are also CD15-positive, CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction.
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cell
Term relations
Equivalent to:
- immature neutrophil and has_part some acidophilic cytoplasm and has_part some azurophil granule and has_part some transcription factor PU.1 and has_part some CCAAT/enhancer-binding protein alpha and has_part some CCAAT/enhancer-binding protein epsilon and has_part some neutrophil gelatinase-associated lipocalin and has_part some lactotransferrin and has_part some myeloperoxidase and has plasma membrane part some integrin alpha-M and has plasma membrane part some alpha-(1,3)-fucosyltransferase FUT4 and has plasma membrane part some CD33 molecule and has plasma membrane part some signal transducer CD24 and has plasma membrane part some aminopeptidase N and lacks_part some tertiary granule and lacks_plasma_membrane_part some low affinity immunoglobulin gamma Fc region receptor III
Subclass of:
- myelocyte
- immature neutrophil
- nongranular leukocyte
- has_part some myeloperoxidase
- lacks_part some tertiary granule
- has_part some acidophilic cytoplasm
- has plasma membrane part some aminopeptidase N
- has plasma membrane part some alpha-(1,3)-fucosyltransferase FUT4
- has_part some azurophil granule
- has plasma membrane part some CD33 molecule
- has_part some CCAAT/enhancer-binding protein epsilon
- has_part some CCAAT/enhancer-binding protein alpha
- lacks_plasma_membrane_part some low affinity immunoglobulin gamma Fc region receptor III
- has_part some neutrophil gelatinase-associated lipocalin
- has plasma membrane part some signal transducer CD24
- has_part some transcription factor PU.1
- has_part some lactotransferrin
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