Terminology Service for NFDI4Health
alveolar macrophage
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http://purl.obolibrary.org/obo/CL_0000583
A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative. [ http://purl.obolibrary.org/obo/go/references/0000031 ]
Term info
Label
alveolar macrophage
Synonyms
- dust cell
comment
Markers: Mouse: F4/80mid, CD11b-/low, CD11c+, CD68+, sialoadhesin+, dectin-1+, MR+, CX3CR1-.
has obo namespace
cell
has related synonym
MF.Lu
Term relations
Equivalent to:
- tissue-resident macrophage and located in some alveolus of lung and has plasma membrane part some integrin alpha-X and has plasma membrane part some C-type lectin domain family 7 member A and has plasma membrane part some adhesion G protein-coupled receptor E1 and has plasma membrane part some sialoadhesin and has plasma membrane part some macrosialin and has plasma membrane part some macrophage mannose receptor 1 and capable of some antigen processing and presentation and has_low_plasma_membrane_amount some integrin alpha-M and lacks_plasma_membrane_part some CX3C chemokine receptor 1
Subclass of:
- tissue-resident macrophage
- material anatomical entity
- lung macrophage
- has plasma membrane part some C-type lectin domain family 7 member A
- has plasma membrane part some macrophage mannose receptor 1
- lacks_plasma_membrane_part some CX3C chemokine receptor 1
- has_low_plasma_membrane_amount some integrin alpha-M
- located in some alveolus of lung
- has plasma membrane part some sialoadhesin
- has plasma membrane part some macrosialin
- has plasma membrane part some adhesion G protein-coupled receptor E1
- capable of some antigen processing and presentation
- has plasma membrane part some integrin alpha-X