Terminology Service for NFDI4Health
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pericyte cell

Go to external page http://purl.obolibrary.org/obo/CL_0000669

An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. [ http://www.ncbi.nlm.nih.gov/pubmed/16807374 https://www.worldcat.org/search?q=bn%3A0721662544 http://www.ncbi.nlm.nih.gov/pubmed/17986482 http://www.ncbi.nlm.nih.gov/pubmed/20024907 ]

Term info

Label

pericyte cell

Synonyms
  • ARC
  • adventitial reticular cell
  • cell of Rouget
  • pericyte
  • pericyte of Rouget
database cross reference
comment

Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.

has alternative id

CL:0000184

has related synonym

adventitial cell