Terminology Service for NFDI4Health

eosinophil

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Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. [ https://www.worldcat.org/search?q=bn%3A0721601464 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626675 http://www.ncbi.nlm.nih.gov/pubmed/1662676 http://www.ncbi.nlm.nih.gov/pubmed/10914487 ]

Term info

Label

eosinophil

Synonyms
  • eosinocyte
  • eosinophilic granulocyte
  • eosinophilic leucocyte
  • eosinophilic leukocyte
database cross reference
comment

Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte.

has broad synonym

polymorphonuclear leucocyte, polymorphonuclear leukocyte