Terminology Service for NFDI4Health
mature B cell
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http://purl.obolibrary.org/obo/CL_0000785
A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. [ https://www.worldcat.org/search?q=bn%3A0781735149 ]
Term info
Label
mature B cell
Synonyms
- mature B lymphocyte
- mature B-cell
- mature B-lymphocyte
comment
Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive.
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cell
Term relations
Equivalent to:
- B cell and capable of some B cell activation and has_completed some mature B cell differentiation
Subclass of:
- B cell
- develops from some transitional stage B cell
- capable of some antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
- capable of some B cell activation
- has_completed some mature B cell differentiation
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