Terminology Service for NFDI4Health
memory B cell
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http://purl.obolibrary.org/obo/CL_0000787
A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative. [ http://purl.obolibrary.org/obo/go/references/0000031 http://en.wikipedia.org/wiki/Memory_B_cell http://www.ncbi.nlm.nih.gov/pubmed/20081059 http://www.ncbi.nlm.nih.gov/pubmed/20839338 https://www.worldcat.org/search?q=bn%3A0781735149 ]
Term info
Label
memory B cell
Synonyms
- memory B lymphocyte
- memory B-cell
- memory B-lymphocyte
comment
Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive.
has obo namespace
cell
Term relations
Equivalent to:
- mature B cell and has plasma membrane part some MHC class II protein complex and has plasma membrane part some membrane-spanning 4-domains subfamily A member 1 and has plasma membrane part some CD27 molecule and has_completed some B cell affinity maturation and lacks_plasma_membrane_part some syndecan-1