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CD4-positive, CD25-positive, alpha-beta regulatory T cell

Go to external page http://purl.obolibrary.org/obo/CL_0000792

A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. [ http://www.ncbi.nlm.nih.gov/pubmed/19464985 https://www.worldcat.org/search?q=bn%3A0781735149 http://www.ncbi.nlm.nih.gov/pubmed/22343568 ]

Term info

Label

CD4-positive, CD25-positive, alpha-beta regulatory T cell

Synonyms
  • CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte
  • CD4-positive, CD25-positive, alpha-beta regulatory T-cell
  • CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte
comment

This cell type is compatible with the HIPC Lyoplate markers for 'Treg'. The inclusion of CD127lo in the logical definition is compatible with both human and mouse T cells of this subtype.

has broad synonym

suppressor T-cell, suppressor T-lymphocyte, Treg, suppressor T lymphocyte, suppressor T cell