Terminology Service for NFDI4Health
CD8-positive, alpha-beta cytotoxic T cell
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http://purl.obolibrary.org/obo/CL_0000794
A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. [ http://purl.obolibrary.org/obo/go/references/0000031 https://www.worldcat.org/search?q=bn%3A0781735149 ]
Term info
Label
CD8-positive, alpha-beta cytotoxic T cell
Synonyms
- CD8-positive, alpha-beta cytotoxic T lymphocyte
- CD8-positive, alpha-beta cytotoxic T-cell
- CD8-positive, alpha-beta cytotoxic T-lymphocyte
comment
Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo.
has broad synonym
cytotoxic T cell, cytotoxic T lymphocyte, killer T-cell, killer T lymphocyte, killer T-lymphocyte, cytotoxic T-cell, cytotoxic T-lymphocyte, killer T cell
has obo namespace
cell
Term relations
Equivalent to:
- CD8-positive, alpha-beta T cell and has_part some perforin-1 and has_part some granzyme B and capable of some T cell mediated cytotoxicity and capable of some granzyme B localization to T cell secretory granule and has_completed some T cell differentiation