Terminology Service for NFDI4Health
DN4 thymocyte
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http://purl.obolibrary.org/obo/CL_0000808
A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive. [ https://www.worldcat.org/search?q=bn%3A0781735149 http://purl.obolibrary.org/obo/go/references/0000031 ]
Term info
Label
DN4 thymocyte
Synonyms
- DN4 alpha-beta immature T lymphocyte
- DN4 alpha-beta immature T-lymphocyte
- DN4 cell
- DN4 immature T cell
- DN4 immature T-cell
- T.DN4.th
- double negative 4
comment
Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and beginning to rearrange the T cell receptor alpha chain.
has broad synonym
early cortical thymocyte
has obo namespace
cell
Term relations
Equivalent to:
- thymocyte and has plasma membrane part some pre-T cell receptor complex and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some CD44 molecule and lacks_plasma_membrane_part some interleukin-2 receptor subunit alpha and lacks_plasma_membrane_part some T cell receptor co-receptor CD8
Subclass of:
- material anatomical entity
- double negative thymocyte
- develops from some DN3 thymocyte
- lacks_plasma_membrane_part some interleukin-2 receptor subunit alpha
- lacks_plasma_membrane_part some CD44 molecule
- has plasma membrane part some pre-T cell receptor complex
Related from: