Terminology Service for NFDI4Health
germinal center B cell
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http://purl.obolibrary.org/obo/CL_0000844
A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation. [ http://www.ncbi.nlm.nih.gov/pubmed/20933013 https://www.worldcat.org/search?q=bn%3A0781735149 http://www.ncbi.nlm.nih.gov/pubmed/19447676 ]
Term info
Label
germinal center B cell
Synonyms
- GC B cell
- GC B lymphocyte
- GC B-cell
- GC B-lymphocyte
- germinal center B lymphocyte
- germinal center B-cell
- germinal center B-lymphocyte
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Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive.
has obo namespace
cell
Term relations
Equivalent to:
- mature B cell and part of some secondary nodular lymphoid tissue and has plasma membrane part some membrane-spanning 4-domains subfamily A member 1