Terminology Service for NFDI4Health
splenic red pulp macrophage
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http://purl.obolibrary.org/obo/CL_0000874
A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low. [ http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/19644016 ]
Term info
Label
splenic red pulp macrophage
comment
Markers: Mouse: F4/80+, CD68+, MR+, Dectin2+, macrosialin+, sialoadhesin-low; role or process: immune, clearance of senescent erythrocytes.
has obo namespace
cell
Term relations
Equivalent to:
- splenic macrophage and part of some red pulp of spleen and has plasma membrane part some C-type lectin domain family 6 member A and has plasma membrane part some adhesion G protein-coupled receptor E1 and has plasma membrane part some macrosialin and has plasma membrane part some macrophage mannose receptor 1 and capable of some immune response and capable of some erythrocyte clearance and has_low_plasma_membrane_amount some integrin alpha-M and has_low_plasma_membrane_amount some sialoadhesin and lacks_plasma_membrane_part some integrin alpha-X
Subclass of:
- splenic macrophage
- material anatomical entity
- has plasma membrane part some macrophage mannose receptor 1
- lacks_plasma_membrane_part some integrin alpha-X
- part of some red pulp of spleen
- has_low_plasma_membrane_amount some integrin alpha-M
- capable of some immune response
- has plasma membrane part some macrosialin
- has_low_plasma_membrane_amount some sialoadhesin
- has plasma membrane part some adhesion G protein-coupled receptor E1
- has plasma membrane part some C-type lectin domain family 6 member A