Terminology Service for NFDI4Health
lymph node subcapsular sinus macrophage
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http://purl.obolibrary.org/obo/CL_0000887
A lymph node macrophage found in the subcapsular sinus of lymph nodes that participates in sensing, clearance, and antigen presentation of lymph-borne particulate antigens. This macrophage is capable of activating invaraint NKT cells and is CD169-positive. [ http://www.ncbi.nlm.nih.gov/pubmed/14668803 http://www.ncbi.nlm.nih.gov/pubmed/20228797 http://www.ncbi.nlm.nih.gov/pubmed/17934446 http://purl.obolibrary.org/obo/go/references/0000031 ]
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Equivalent to:
- lymph node macrophage and has plasma membrane part some sialoadhesin and capable of some positive regulation of natural killer cell activation and adjacent_to some capsule of lymph node