Terminology Service for NFDI4Health
naive T cell
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http://purl.obolibrary.org/obo/CL_0000898
Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. [ http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/19100699 ]
Term info
Label
naive T cell
Synonyms
- naive T lymphocyte
- naive T-cell
- naive T-lymphocyte
has obo namespace
cell
Term relations
Equivalent to:
- mature T cell and has plasma membrane part some receptor-type tyrosine-protein phosphatase C isoform CD45RA and has plasma membrane part some C-C chemokine receptor type 7 and has plasma membrane part some interleukin-7 receptor subunit alpha and has_completed some T cell selection and has_high_plasma_membrane_amount some L-selectin and has_low_plasma_membrane_amount some CD44 molecule
Subclass of:
- mature T cell
- has plasma membrane part some C-C chemokine receptor type 7
- has plasma membrane part some interleukin-7 receptor subunit alpha
- has_high_plasma_membrane_amount some L-selectin
- has_low_plasma_membrane_amount some CD44 molecule
- has plasma membrane part some receptor-type tyrosine-protein phosphatase C isoform CD45RA