Terminology Service for NFDI4Health
Tc1 cell
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http://purl.obolibrary.org/obo/CL_0000917
A CD8-positive, alpha-beta positive T cell that has the phenotype T-bet-positive, eomesodermin-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. [ http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/9914231 http://www.ncbi.nlm.nih.gov/pubmed/22343568 ]
Term info
Label
Tc1 cell
Synonyms
- T-cytotoxic T cell type 1
- Tc1 CD8+ T cell
- Tc1 T cell
- Tc1 T lymphocyte
- Tc1 T-cell
- Tc1 T-lymphocyte
comment
This cell type is compatible with the HIPC Lyoplate markers for 'Tc1 CD8+ T cell', but its logical definition includes additional known characteristics of Tc1 T cells.
has obo namespace
cell
Term relations
Equivalent to:
- CD8-positive, alpha-beta cytokine secreting effector T cell and has_part some T-box transcription factor TBX21 and has_part some eomesodermin and has plasma membrane part some C-X-C chemokine receptor type 3 and capable of some interferon-gamma production and lacks_plasma_membrane_part some C-C chemokine receptor type 6
Subclass of:
- CD8-positive, alpha-beta cytokine secreting effector T cell
- lacks_plasma_membrane_part some C-C chemokine receptor type 6
- has_part some eomesodermin
- capable of some interferon-gamma production
- has_part some T-box transcription factor TBX21
- has plasma membrane part some C-X-C chemokine receptor type 3