Terminology Service for NFDI4Health

type I NK T cell

Go to external page http://purl.obolibrary.org/obo/CL_0000921


An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d. [ http://www.ncbi.nlm.nih.gov/pubmed/15039760 http://purl.obolibrary.org/obo/go/references/0000031 ]

Term info

Label

type I NK T cell

Synonyms
  • classical NK T cell
  • type I NK T lymphocyte
  • type I NK T-cell
  • type I NK T-lymphocyte
  • type I NKT cell
comment

In mouse the canonical TCR is V-alpha-14, and in humans it is V-alpha 24.

has related synonym

invariant NK T cell