Terminology Service for NFDI4Health
early lymphoid progenitor
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http://purl.obolibrary.org/obo/CL_0000936
A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative. [ http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/19022770 ]
Term info
Label
early lymphoid progenitor
Synonyms
- ELP
- LMPP
- lymphoid-primed multipotent progenitor
comment
Markers are associated with mouse cells. ELP transcription factors include E2A-positive, Ikaros-positive, EBF-negative, Pax5-negative, PU.1-negative.
has obo namespace
cell
has related synonym
GMLP
Term relations
Equivalent to:
- hematopoietic multipotent progenitor cell and has plasma membrane part some receptor-type tyrosine-protein kinase FLT3 and has plasma membrane part some mast/stem cell growth factor receptor and has plasma membrane part some lymphocyte antigen 6A-2/6E-1 and capable of some lymphocyte differentiation and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some glycophorin-A
Subclass of:
- hematopoietic multipotent progenitor cell
- precursor cell
- develops from some Slamf1-negative multipotent progenitor cell
- has plasma membrane part some lymphocyte antigen 6A-2/6E-1
- lacks_plasma_membrane_part some glycophorin-A
- has plasma membrane part some receptor-type tyrosine-protein kinase FLT3
- has plasma membrane part some mast/stem cell growth factor receptor
- capable of some lymphocyte differentiation