Terminology Service for NFDI4Health
small pre-B-II cell
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http://purl.obolibrary.org/obo/CL_0000954
A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. [ http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/16551251 http://www.ncbi.nlm.nih.gov/pubmed/18432934 http://www.ncbi.nlm.nih.gov/pubmed/9785673 ]
Term info
Label
small pre-B-II cell
Synonyms
- small pre-BII cell
comment
Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.
has obo namespace
cell
Term relations
Equivalent to:
- pre-B-II cell and has_part some V(D)J recombination-activating protein 1 and has_part some V(D)J recombination-activating protein 2 and participates_in some immunoglobulin light chain V-J recombination and lacks_plasma_membrane_part some B cell receptor complex and lacks_plasma_membrane_part some pre-B cell receptor complex
Subclass of:
- pre-B-II cell
- participates_in some immunoglobulin light chain V-J recombination
- lacks_plasma_membrane_part some pre-B cell receptor complex
- has_part some V(D)J recombination-activating protein 1
- lacks_plasma_membrane_part some B cell receptor complex
- has_part some V(D)J recombination-activating protein 2
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