Terminology Service for NFDI4Health
T1 B cell
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http://purl.obolibrary.org/obo/CL_0000958
A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative. [ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193793 http://www.ncbi.nlm.nih.gov/pubmed/12810111 http://purl.obolibrary.org/obo/go/references/0000031 ]
Term info
Label
T1 B cell
Synonyms
- T1 B lymphocyte
- T1 B-cell
- T1 B-lymphocyte
- transitional stage 1 B cell
comment
T1 B cells are also reportedly CD10-negative/positive??, CD20-positive, CD24-positive, CD38-positive, CD48-positive, CD84-positive, CD150-positive, CD244-negative, and CD352-positive.
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cell
Term relations
Equivalent to:
- transitional stage B cell and has plasma membrane part some complement component C1q receptor and lacks_plasma_membrane_part some IgD immunoglobulin complex and lacks_plasma_membrane_part some L-selectin and lacks_plasma_membrane_part some complement receptor type 2 and lacks_plasma_membrane_part some low affinity immunoglobulin epsilon Fc receptor
Subclass of:
- transitional stage B cell
- has plasma membrane part some complement component C1q receptor
- lacks_plasma_membrane_part some IgD immunoglobulin complex
- lacks_plasma_membrane_part some complement receptor type 2
- lacks_plasma_membrane_part some L-selectin
- lacks_plasma_membrane_part some low affinity immunoglobulin epsilon Fc receptor
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