Terminology Service for NFDI4Health
Bm3 B cell
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http://purl.obolibrary.org/obo/CL_0000965
A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type. [ http://www.ncbi.nlm.nih.gov/pubmed/18432934 http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/8006591 ]
Term info
Label
Bm3 B cell
Synonyms
- Bm3 B lymphocyte
- Bm3 B-cell
- Bm3 B-lymphocyte
comment
Bm3 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-negative, CD71-positive, and CD77-positive.
has obo namespace
cell
has related synonym
centroblast
Term relations
Equivalent to:
- germinal center B cell and has plasma membrane part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and has plasma membrane part some lactosylceramide 4-alpha-galactosyltransferase and capable of some somatic hypermutation of immunoglobulin genes and lacks_plasma_membrane_part some IgD immunoglobulin complex
Subclass of:
- germinal center B cell
- capable of some somatic hypermutation of immunoglobulin genes
- lacks_plasma_membrane_part some IgD immunoglobulin complex
- has plasma membrane part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- develops from some Bm2' B cell
- has plasma membrane part some lactosylceramide 4-alpha-galactosyltransferase
Related from: