Terminology Service for NFDI4Health
unswitched memory B cell
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http://purl.obolibrary.org/obo/CL_0000970
An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative. [ https://www.worldcat.org/search?q=bn%3A0781765196 http://www.ncbi.nlm.nih.gov/pubmed/20933013 http://www.ncbi.nlm.nih.gov/pubmed/22343568 http://purl.obolibrary.org/obo/go/references/0000031 ]
Term info
Label
unswitched memory B cell
Synonyms
- unswitched memory B lymphocyte
- unswitched memory B-cell
- unswitched memory B-lymphocyte
comment
This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.
has broad synonym
IgD+ memory B cell
has obo namespace
cell
Term relations
Equivalent to:
- memory B cell and has plasma membrane part some IgD immunoglobulin complex and has plasma membrane part some IgM immunoglobulin complex and has plasma membrane part some CD27 molecule and lacks_plasma_membrane_part some IgG immunoglobulin complex and lacks_plasma_membrane_part some IgE immunoglobulin complex and lacks_plasma_membrane_part some IgA immunoglobulin complex and lacks_plasma_membrane_part some syndecan-1
Subclass of:
- memory B cell
- lacks_plasma_membrane_part some IgG immunoglobulin complex
- lacks_plasma_membrane_part some IgA immunoglobulin complex
- develops from some plasmablast
- has plasma membrane part some IgD immunoglobulin complex
- has plasma membrane part some IgM immunoglobulin complex
- lacks_plasma_membrane_part some IgE immunoglobulin complex
Related from: