Terminology Service for NFDI4Health
class switched memory B cell
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http://purl.obolibrary.org/obo/CL_0000972
A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface. [ https://www.worldcat.org/search?q=bn%3A0781765196 http://www.ncbi.nlm.nih.gov/pubmed/9295047 http://www.ncbi.nlm.nih.gov/pubmed/20933013 http://purl.obolibrary.org/obo/go/references/0000031 ]
Term info
Label
class switched memory B cell
Synonyms
- class switched memory B lymphocyte
- class switched memory B-cell
- class switched memory B-lymphocyte
comment
Per DSD: Class switched memory B cells are also reportedly CD48-positive, CD229-positive, and CD352-positive.
has obo namespace
cell
Term relations
Equivalent to:
- memory B cell and has plasma membrane part some CD27 molecule and has_completed some isotype switching and lacks_plasma_membrane_part some IgM immunoglobulin complex
Subclass of:
- memory B cell
- has_completed some isotype switching
- lacks_plasma_membrane_part some IgM immunoglobulin complex
- develops from some unswitched memory B cell