Terminology Service for NFDI4Health
long lived plasma cell
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http://purl.obolibrary.org/obo/CL_0000974
A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow. [ http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/16014527 https://www.worldcat.org/search?q=bn%3A9780781765190 ]
Term info
Term relations
Equivalent to:
- plasma cell and has_high_plasma_membrane_amount some C-X-C chemokine receptor type 4 and has_high_plasma_membrane_amount some syndecan-1 and has_low_plasma_membrane_amount some CD19 molecule and lacks_plasma_membrane_part some immunoglobulin complex and lacks_plasma_membrane_part some MHC class II protein complex and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Subclass of:
- plasma cell
- has_low_plasma_membrane_amount some CD19 molecule
- has_high_plasma_membrane_amount some C-X-C chemokine receptor type 4
- has_high_plasma_membrane_amount some syndecan-1
- develops from some short lived plasma cell
- lacks_plasma_membrane_part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1